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Index > Protein center > GFPT1(Gene name) > Human
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  • GFPT1 (Gene name),
  • Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Protein name ),  GFPT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GFPT1(GFAT;GFPT);
    Protein name:
    Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1;
    Alternative:
    Glutamine:fructose 6 phosphate amidotransferase 1(GFAT 1;GFAT1);D-fructose-6-phosphate amidotransferase 1;Hexosephosphate aminotransferase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    699
    Sequence:
    50:
    MCGIFAYLNY | HVPRTRREIL | ETLIKGLQRL | EYRGYDSAGV | GFDGGNDKDW | 
    100:
    EANACKIQLI | KKKGKVKALD | EEVHKQQDMD | LDIEFDVHLG | IAHTRWATHG | 
    150:
    EPSPVNSHPQ | RSDKNNEFIV | IHNGIITNYK | DLKKFLESKG | YDFESETDTE | 
    200:
    TIAKLVKYMY | DNRESQDTSF | TTLVERVIQQ | LEGAFALVFK | SVHFPGQAVG | 
    250:
    TRRGSPLLIG | VRSEHKLSTD | HIPILYRTAR | TQIGSKFTRW | GSQGERGKDK | 
    300:
    KGSCNLSRVD | STTCLFPVEE | KAVEYYFASD | ASAVIEHTNR | VIFLEDDDVA | 
    350:
    AVVDGRLSIH | RIKRTAGDHP | GRAVQTLQME | LQQIMKGNFS | SFMQKEIFEQ | 
    400:
    PESVVNTMRG | RVNFDDYTVN | LGGLKDHIKE | IQRCRRLILI | ACGTSYHAGV | 
    450:
    ATRQVLEELT | ELPVMVELAS | DFLDRNTPVF | RDDVCFFLSQ | SGETADTLMG | 
    500:
    LRYCKERGAL | TVGITNTVGS | SISRETDCGV | HINAGPEIGV | ASTKAYTSQF | 
    550:
    VSLVMFALMM | CDDRISMQER | RKEIMLGLKR | LPDLIKEVLS | MDDEIQKLAT | 
    600:
    ELYHQKSVLI | MGRGYHYATC | LEGALKIKEI | TYMHSEGILA | GELKHGPLAL | 
    650:
    VDKLMPVIMI | IMRDHTYAKC | QNALQQVVAR | QGRPVVICDK | EDTETIKNTK | 
    699:
    RTIKVPHSVD | CLQGILSVIP | LQLLAFHLAV | LRGYDVDFPR | NLAKSVTVE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    Pfam:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    E10569h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    E10569m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    E10569r
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    U10569h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    U10569m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    U10569r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    P10569Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    P10569Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Cat.:
    P10569Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Monoclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Monoclonal Antibody for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Protein for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Protein for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Protein for Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1

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    Linearity
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    References
    1. 1.
      "Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase."
      McKnight G.L. , Mudri S.L. , Mathewes S.L. , Traxinger R.R. , Marshall S. , Sheppard P.O. , O'Hara P.J.
      J. Biol. Chem.267:25208-25212(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "A novel variant of glutamine:fructose-6-phosphate amidotransferase-1 (GFAT1) mRNA is selectively expressed in striated muscle."
      DeHaven J.E. , Robinson K.A. , Nelson B.A. , Buse M.G.
      Diabetes50:2419-2424(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 124-275 (ISOFORM 1);TISSUE SPECIFICITY
    5. 5.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    9. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    12. 12.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes."
      Nakaishi Y. , Bando M. , Shimizu H. , Watanabe K. , Goto F. , Tsuge H. , Kondo K. , Komatsu M.
      FEBS Lett.583:163-167(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 332-699;SUBUNIT;SUBSTRATE-BINDING SITES
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMSTA1 ALA-15; MET-15; VAL-43; CYS-111; THR-121; PHE-199; TYR-366; HIS-403; HIS-452; THR-509; THR-510; TRP-514 AND TRP-530
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